- Apr 07, 2016 -
Ribosome synthesis in addition to other than the proteins necessary for life, is also involved in many types of polypeptide synthesis of small molecule compounds. This peptide small molecule compounds have a wide range of structures and biological diversity for human anti-tumor and anti-inflammation drug discovery and research provides a broad prospect.
Recently, Department of chemistry, University researchers and their collaborators illustrated Zhang Qi phomopsin biosynthesis mechanism of antitumor peptides, and discover the ascus fungi have a huge capacity to produce similar compounds. Related research "widespread pathway for ribosomal Biosynthetic investigation of phomopsins reveals a natural products in Ascomycetes" published in top international journals in the United States journal proceedings of the National Academy of Sciences (Proceedings of the National Academy of Sciences of the United States of America. 2016, DOI:10.1073/pnas.1522907113).