GMP factory supply Rapamycin / Sirolimus CAS NO: 53123-88-9

GMP factory supply Rapamycin / Sirolimus CAS NO: 53123-88-9

Sinoway Industrial Co.,Ltd is a famous China rapamycin manufacturer and supplier, welcome to buy GMP and EP rapamycin from us and check the price with us. 1.Quick details of Rapamycin ( Sirolimus ): Product name: Rapamycin Other name:Sirolimus CAS No: 53123-88-9 Molecular Formula : C51H79NO13...

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Product Details

GMP factory supply Rapamycin / Sirolimus CAS NO: 53123-88-9

1.Quick details of Rapamycin ( Sirolimus ):

Product name: Rapamycin

Other name:Sirolimus

CAS No: 53123-88-9

Molecular Formula : C51H79NO13

Molecular Weight: : 914.18

Appearance: off-white to yellow crystalline powder

Purity: 99% min

2. COA of Rapamycin:

TEST ITEMS

SPECIFICATION

RESULTS

Appearance

White or off-white crystal powder, odorless

Conform

Identification

IR spectrum is concordant with reference spectrum of Sirolimus RS.

Conform

HPLC:The retention time is complied with that of reference substance.

Conform

Water

≤2.0%

0.2%

Heavy metals

≤20 ppm

<20ppm

Chromtographic purity

Isomer A≤1.0%

0.2 %

Isomer C≤5.0%

1.9 %

Any other individual impurity≤0.5 %

0.3 %

Total impurity(Excluding isomerA&C)≤3.0%

0.5%

Assay(dried substance)

98.0% ~ 102.0%

99.4%

Residual solvents

n-Hexane ≤290ppm

<290ppm

Acetone ≤5000ppm

<5000ppm

Acetoacetate ≤5000ppm

<5000ppm

Butyl Acetate ≤5000ppm

<5000ppm

3.Application ofRapamycin / Sirolimus:

Rapamycin is a triene macrolide antibiotic, which demonstrates

anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins. Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.


More details pls contact with me......


Ms. Serein Yan
International Sales Department
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Sinoway Industrial Co., Ltd.  (29 years, ISO9001:2008 and SGS certified)

Add: 16/F., Huicheng Comm. Complex, No.839 Xiahe Rd, Xiamen, China (Postal Code: 361004)
Tel: 0086-592-5887162  Fax: 0086-592-5854960
E-mail:
serein@china-sinoway.com
Skype: serein95   , Mobile/ Wechat / Whats App: 0086-15060741657

Specializing in the research, development and custom manufacturing of gmp factory supply rapamycin / sirolimus cas no: 53123-88-9, SINOWAY, though situated in China, enjoys good reputation among international customers. We supply you with pure natural and well extracted products which can give the best care.

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