Spironolactone Spironolact CAS NO 52-01-7

Spironolactone Spironolact CAS NO 52-01-7

Sinoway Industrial Co.,Ltd is a famous China spironolactone manufacturer and supplier, welcome to buy GMP and EP spironolactone from us and check the price with us. Basic information: Product Name: Spironolactone Molecular Formula : C24H32O4S Molecular Weight: 416.57 CAS No.: 52-01-7 Appearance:...

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Product Details

Spironolactone Spironolact CAS NO 52-01-7

Basic information:

Product Name: Spironolactone
Molecular Formula : C24H32O4S
Molecular Weight: 416.57

CAS No.: 52-01-7

Appearance: White powder

Specifications:

EP8/USP38

Usages :

1) Treat for High blood pressure

2) Treat for primary hyperaldosteronism.

3) Treat for Hypokalemia (Potassium deficiency

4) Severe heart failure

5) Edema (fluid retention) from various conditions,

including Congestive edema; Liver cirrhosis ascites; renal edema

6) As cosmetic, Spironolactone have an effect in hair grow.


ITEMS

STANDARDS

RESULTS

Appearance (Ph.Eur.)

A white or yellowish-white powder

White powder

Solubility (Ph.Eur.)

Practically insoluble in water, soluble in ethanol (96%)

Complies

Identification

  1. IR –spectrum (Ph.Eur.)

A.  IR –spectrum (USP)

  1. TLC (Ph.Eur.)

B.  UV absorption (USP)

  1. Colour reaction (Ph.Eur.)

C.  Precipitate reaction (USP)

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Meet the requirement

Complies

Complies

Complies

Complies

Complies

Complies

Loss on drying

(Ph.Eur.)

(USP)


Not more than 0.5%

Not more than 0.5%


0.24%

0.23%

Specific optical rotation

(Ph.Eur.)

(USP)


-41° ~-46°

-41° ~-45°


-43.4°

-44.3°

Sulphated ash (Ph.Eur.)

≤0.1%

0.02%

Related substances (Ph.Eur.)

Impurity A

Impurity B

Impurity C

Impurity D

Impurity E

Impurity I

Any unspecified impurity

Total

≤0.2%

≤0.3%

≤0.2%

≤0.15%

≤0.3%

≤0.5%

≤0.10%

≤0.7%

N.D.

N.D.

N.D.

N.D.

N.D.

0.07%

Complies

0.16%

Ordinary impurities (USP)

≤2.0%

Complies

Free thiol compounds (Ph.Eur.)

≤0.05mL

Complies

Free mercapto compounds (USP)

≤0.10mL

Complies

Chromium (Ph.Eur.)

≤50ppm

Complies

Assay

HPLC (Ph.Eur.)

HPLC (USP)


97.5%~102.0%

97.5%~103.0%


100.2%

99.8%

Residual solvent (In-house)

Methanol

Tetrahydrofuran

DMF


≤3000ppm

≤720ppm

≤880ppm


56ppm

≤LOD (0.0046ppm)

≤LOD (0.23ppm)

Particle size (In-house)

95% ≤ 20 microns

Complies

Conclusion

Compiles with EP8/USP38



Contacts:

Ms. Lvky Lv

Email: lv@china-sinoway.com

Tel: 0086-0592-5887165

Mob/WhatsApp/Wechat: 0086-18350268056

Skype: lvyundan33



Specializing in the research, development and custom manufacturing of spironolactone spironolact cas no 52-01-7, SINOWAY, though situated in China, enjoys good reputation among international customers. We supply you with pure natural and well extracted products which can give the best care.

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