Zidovudine CAS:30516-87-1

Zidovudine CAS:30516-87-1

Product Name: Zidovudine Chemical Name: 1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione CAS: 30516-87-1 Molecular Formula: C10H13N5O4 Molecular Weight: 267.25 Specification Use: Anti-Aids API Zidovudine (INN) or azidothymidine (AZT) (also called...

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Product Details

Product Name: Zidovudine
Chemical Name:  
1-[(2R,4S,5S)-4-Azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4-(1H,3H)-dione

CAS: 30516-87-1

Molecular Formula: C10H13N5O4 
Molecular Weight:  267.25 

 

Specification

TESTS

STANDARDS (USP/EP)

APPEARANCE

WHITE TO   YELLOWISH CRYSTALLINE POWDER

SOLUBILITY

SPARINGLY SOLUBLE IN   WATER,FREELY SOLUBLE IN METHANOL, SOLUBLE IN ETHANOL

IDENTIFICATION

A: IR

B: HPCL

MELTING POINT

118MIN

SPECIFIC ROTATION

+60.5º TO 63.0º

WATER

1.0%MAX

RESIDUE ON IGNITION

0.25%MAX

TOTAL IMPURITIES

1.0%MAX

HEAVY METALS

10PPM MAX

ASSAY

97-102.0%

 

Use: Anti-Aids API

Zidovudine (INN) or azidothymidine (AZT) (also called ZDV) is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the first clinically proven successful treatment of HIV/AIDS infectiousness. It is a therapeutic analog of thymidine that targets HIV exclusively. It remains in widespread use today and is recognized by the Centers for Disease Control as one of the most effective drugs in medical history.


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