Carbidopa

Carbidopa

Sinoway Industrial Co.,Ltd is a famous China carbidopa manufacturer and supplier, welcome to buy GMP and EP carbidopa from us and check the price with us. Basic information ofCarbidopa: Use of Carbidopa: For various causes Parkinson's disease. COA ofCarbidopa:

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Product Details

Basic information ofCarbidopa:

Name

Carbidopa

Alias

1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)-decahydroquinoxaline

CAS Number

38821-49-7

Molecular Formula

C10H16N2O5

Molecular Weight

244.24

QualityStandard

USP32

Package Size

25kg/drum, according your requirement

Brief Introduction

Carbidopa with strong outer peripheral dopa decarboxylase inhibitors. Easy through the blood-brain barrier, in combination with levodopa, it suppresses only the outer peripheral dopa decarboxylase activity, reducing the production of dopamine in peripheral tissues, reduce adverse reactions outer periphery, thereby enabling an increase in levodopa into the hub, improve brain concentration of dopamine, enhance the efficacy of levodopa, it is an important adjunct to levodopa. Carbidopa alone invalid, clinical carbidopa and levodopa is usually 1:10 or 1: 4 Proportion compound preparation

Use of Carbidopa:

For various causes Parkinson's disease.

COA ofCarbidopa:

ITEMS

SPECIFICATION

RESULTS

Appearance

A white or creamy white powder

Creamy white powder

Identification

IR


HPLC


IR spectrum is consistent with carbidopa CRS

Conform with the retention time of the major peak in the chromatogram


Conforms


Conforms

Specific rotation

-21.0º ~-23.5º

-22.7º

Loss on drying

6.9%-7.9%

7.4%

Residue on ignition

≤0.1%

0.05%

Heavy metals

≤0.001%

<0.001%

Limit of methyldopa and carbidopa related components A

Methyldopa

Carbidopa related components A

Any unknown impurity

≤0.5%

≤0.5%


≤0.10%

0.26%

<LOD(0.02%)


0.09%

Residual solvents

Trichloromethane

Ethanol


≤0.006%

≤0.10%


<LOD (0.4PPM)

0.0001%

ASSAY

98.0%--102.0%

100.1%

Conclusion:The batch conforms to USP32 specifications.

Specializing in the research, development and custom manufacturing of carbidopa, SINOWAY, though situated in China, enjoys good reputation among international customers. We supply you with pure natural and well extracted products which can give the best care.

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